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Comparative Study on Remineralizing Ability of Casein Phosphopeptide Amorphous Calcium Phosphate and β-Tricalcium Phosphate on Dental Erosion: An In vitro Atomic Force Microscope Study

Padma Gandi*,Mousumi ,Sangeeta Meena,Pallavi Waghmare

Aim: To compare the remineralizing ability of between casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and β-tricalcium phosphate (β-TCP) on dental erosion by soft drinks in human tooth enamel using atomic force microscope.
Materials and methods: 40 extracted human anterior teeth which were randomly divided into two groups: CPPACP paste (GC Tooth Mousse) and β-TCP (ClinproTM Tooth Crèam) paste demineralized in soft drink (Coca-Cola) for 2 min followed by remineralization by both pastes. Each sample was subjected to atomic force microscopy (AFM) for unexposed, demineralization and remineralization cycle for surface roughness determination.
Results and statistical analysis: Both experimental groups of samples shows remineralization that is reduction in surface roughness which was higher with β-TCP paste. Statistical analysis was performed using Student unpaired t-test and ANOVA along with Tukey's post HOC analysis with p<0.01 in intra group comparison and not significant inter group comparison.
Conclusion: The β-TCP mineralizing paste is effective on preventing dental erosion.