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Comparing the Effect of One Stage Full Mouth Disinfection Versus Quadrant-Wise Scaling and Root Planing on Clinical Parameters and Salivary Inflammatory Biomarkers in Chronic Periodontitis Patients

Eskandari A,Babaloo Z,Shirmohammadi A*,Khashabi E

Background: We aimed to compare the efficacy of one stage full mouth disinfection versus the quadrant-wise scaling and root planing in terms of clinical parameters and inflammatory biomarkers screening.
Methods: Forty patients, with generalized moderate to severe chronic periodontitis, participated in the study. The test group received one stage full mouth disinfection (FMD). Quadrant wise scaling and root planing (Q-SRP) was performed for the control group. At baseline, 2 months and 4 months, Clinical parameters and salivary IL-1β and MMP-8 were measured.
Results: Both procedures resulted in statistically significant improvement in all of the measured parameters between the baseline and the 2 and 4 months (p<0.05%). No meaningful improvement was seen between the 2 and 4 months (p<0.05%) in both of the FMD and Q-SRP groups. There was no significantly difference between the study groups except for the MGI (P<0.05).
Conclusion: No statistically significant differences were found between FMD and Q-SRP.