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Toxicological effects of leather dyes on total leukocyte count of fresh water teleost, Cirrhinus mrigala (Ham)

Sheikh Afaq, KS Rana

The experiment were conducted on fresh water fish Cirrhinus mrigala (Ham.) in the Dept. of zoology Agra college Agra to check out the effect of two leather dyes Bismarck brown and Acid leather brown on Total leucocyte count with three conc. From both the dyes as 0.6 mg/l, 0.7 mg/l and 0.7 mg/l for Bismarck brown and 8 mg/l, 9 mg/l and 10 mg/l for Acid leather brown at different time intervals (24 hrs, 48 hrs, 96 hrs and 1 week), however the effect was more with Acid leather brown exposure than Bismarck brown. The increasing trend in TLC on exposure to Bismarck brown and acid leather brown at different time intervals and at all three concentrations has been observed. The sub-lethal exposure of Bismarck brown and Acid leather brown results into significant increase in the TLC. Intoxication of Bismarck brown and acid leather brown induces leukocytosis in which TLC increases. Leukocytosis in some cases may be due to protective reaction in which leukocyte protects the body when foreign substances (in present study fungicide invade the body. The increase in number of leukocyte may also be found in leukemia. The aim of the study is to aware the people to protect the fish fauna from leather dye effect. The study is to aware people to check the pollution related to leather industries.